ctcRbase

Entry Detail

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General Information

Database ID: BRCA04498 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: RAB21 Full Name: RAB21, member RAS oncogene family Category: mRNA Synonyms: - Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 71754874 End Site(bp): 71800285 Gene Summary: This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015] External Links: Ensembl ID: ENSG00000080371 HGNC ID: HGNC:18263 Entrez Gene: 23011

Expression Profile of RAB21 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-129-5p YES YES YES hsa-miR-1297 YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-134-5p YES YES YES hsa-miR-140-3p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-183-5p YES YES YES hsa-miR-186-5p YES YES YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-208a-3p YES NO YES hsa-miR-208b-3p YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-326 YES NO YES hsa-miR-330-5p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES YES hsa-miR-411-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-448 YES YES YES hsa-miR-452-5p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES NO YES hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-93-5p YES YES YES Display: