ctcRbase

Entry Detail

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General Information

Database ID: BRCA04545 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: CUL3 Full Name: cullin 3 Category: mRNA Synonyms: CUL-3|PHA2E Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 224470150 End Site(bp): 224585397 Gene Summary: This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] External Links: Ensembl ID: ENSG00000036257 HGNC ID: HGNC:2553 Entrez Gene: 8452

Expression Profile of CUL3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES NO YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-137 YES NO YES hsa-miR-139-5p YES NO YES hsa-miR-140-5p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-144-3p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-186-5p YES NO YES hsa-miR-200a-3p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-299-3p YES NO YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-32-5p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-367-3p YES YES YES hsa-miR-371a-5p YES NO YES hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-454-3p YES YES YES hsa-miR-455-3p YES NO YES hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-543 YES NO YES hsa-miR-93-5p YES YES YES Display: