ctcRbase

Entry Detail

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General Information

Database ID: BRCA04552 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HADHA Full Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Category: mRNA Synonyms: ECHA|GBP|HADH|LCEH|LCHAD|MTPA|TP-ALPHA Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 26190635 End Site(bp): 26244726 Gene Summary: This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000084754 HGNC ID: HGNC:4801 Entrez Gene: 3030

Expression Profile of HADHA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-506-3p YES YES NO Display: