ctcRbase

Entry Detail

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General Information

Database ID: BRCA04562 Cancer Type: breast cancer Dataset: GSE86978 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: LIMS1 Full Name: LIM zinc finger domain containing 1 Category: mRNA Synonyms: PINCH|PINCH-1|PINCH1 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 108534355 End Site(bp): 108687246 Gene Summary: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] External Links: Ensembl ID: ENSG00000169756 HGNC ID: HGNC:6616 Entrez Gene: 3987

Expression Profile of LIMS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p NO YES YES hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-153-3p YES NO YES hsa-miR-15a-5p NO NO YES hsa-miR-15b-5p NO NO YES hsa-miR-16-5p NO NO YES hsa-miR-182-5p NO YES YES hsa-miR-195-5p NO NO YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-29a-3p NO YES YES hsa-miR-29b-3p NO YES YES hsa-miR-29c-3p NO YES YES hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-409-3p YES NO YES hsa-miR-424-5p NO NO YES hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-448 YES NO YES hsa-miR-497-5p NO NO YES hsa-miR-505-3p YES YES NO hsa-miR-543 YES YES NO Display: