ctcRbase

Entry Detail

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General Information

Database ID: BRCA04605 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: CAST Full Name: calpastatin Category: mRNA Synonyms: BS-17|PLACK Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 96525267 End Site(bp): 96779595 Gene Summary: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] External Links: Ensembl ID: ENSG00000153113 HGNC ID: HGNC:1515 Entrez Gene: 831

Expression Profile of CAST Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-145-5p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-152-3p YES YES NO hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-186-5p YES YES YES hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-195-5p YES NO YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-375 YES NO YES hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES NO YES hsa-miR-429 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-455-5p YES YES YES hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-497-5p YES NO YES hsa-miR-503-5p YES NO YES hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-873-5p YES YES NO Display: