ctcRbase

Entry Detail

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General Information

Database ID: BRCA04646 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: NUDT5 Full Name: nudix hydrolase 5 Category: mRNA Synonyms: YSA1|YSA1H|YSAH1|hNUDT5 Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 12165325 End Site(bp): 12196144 Gene Summary: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013] External Links: Ensembl ID: ENSG00000165609 HGNC ID: HGNC:8052 Entrez Gene: 11164

Expression Profile of NUDT5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-183-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-382-5p YES YES NO Display: