ctcRbase

Entry Detail

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General Information

Database ID: BRCA04667 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PPHLN1 Full Name: periphilin 1 Category: mRNA Synonyms: CR|HSPC206|HSPC232 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 42238447 End Site(bp): 42459715 Gene Summary: The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000134283 HGNC ID: HGNC:19369 Entrez Gene: 51535

Expression Profile of PPHLN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-141-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-496 YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-9-5p YES YES NO Display: