ctcRbase

Entry Detail

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General Information

Database ID: BRCA04694 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: KARS Full Name: lysyl-tRNA synthetase Category: mRNA Synonyms: CMTRIB|DFNB89|KARS1|KARS2|KRS Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 75627474 End Site(bp): 75648643 Gene Summary: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000065427 HGNC ID: HGNC:6215 Entrez Gene: 3735

Expression Profile of KARS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO Display: