ctcRbase

Entry Detail

General Information

Database ID:	BRCA04717
Cancer Type:	breast cancer
Dataset:	GSE111065
CTCs/CTM Isolation Method:	microfluidics immunofluorescence

Gene Information

ncRNA Symbol:

PEA15

Full Name:

proliferation and apoptosis adaptor protein 15

Category:

mRNA

Synonyms:

Chromosome:

chr1

Strand:

Coordinate:

Start Site(bp):

160205337

End Site(bp):

160215376

Gene Summary:

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

External Links:

Ensembl ID:	ENSG00000162734
HGNC ID:	HGNC:8822
Entrez Gene:	8682

Expression Profile of PEA15 Gene

Regulatory Relationship

mRNA targets:

miRNA targets:

miRNA Name	PITA	miRanda	RNAhybrid
hsa-miR-10a-5p	YES	YES	YES
hsa-miR-10b-5p	YES	YES	YES
hsa-miR-124-3p	YES	NO	YES
hsa-miR-129-5p	YES	YES	NO
hsa-miR-130a-3p	YES	YES	NO
hsa-miR-130b-3p	YES	YES	NO
hsa-miR-132-3p	YES	YES	YES
hsa-miR-141-3p	YES	YES	NO
hsa-miR-148a-3p	YES	YES	NO
hsa-miR-148b-3p	YES	YES	NO
hsa-miR-149-5p	YES	NO	YES
hsa-miR-152-3p	YES	YES	NO
hsa-miR-155-5p	YES	YES	YES
hsa-miR-185-5p	YES	YES	NO
hsa-miR-19a-3p	YES	NO	YES
hsa-miR-19b-3p	YES	NO	YES
hsa-miR-200a-3p	YES	YES	NO
hsa-miR-212-3p	YES	YES	YES
hsa-miR-216a-5p	YES	YES	NO
hsa-miR-217	YES	YES	NO
hsa-miR-24-3p	YES	YES	YES
hsa-miR-28-3p	YES	NO	YES
hsa-miR-301a-3p	YES	YES	NO
hsa-miR-301b-3p	YES	YES	NO
hsa-miR-329-3p	YES	NO	YES
hsa-miR-339-5p	YES	YES	YES
hsa-miR-34a-5p	YES	YES	YES
hsa-miR-34c-5p	YES	YES	YES
hsa-miR-362-3p	YES	NO	YES
hsa-miR-449a	YES	YES	YES
hsa-miR-449b-5p	YES	YES	YES
hsa-miR-454-3p	YES	YES	NO
hsa-miR-485-5p	YES	NO	YES
hsa-miR-491-5p	YES	YES	NO
hsa-miR-493-3p	YES	NO	YES
hsa-miR-541-3p	YES	NO	NO
hsa-miR-654-5p	YES	NO	NO

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