ctcRbase

Entry Detail

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General Information

Database ID: BRCA04734 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: EDA Full Name: ectodysplasin A Category: mRNA Synonyms: ECTD1|ED1|ED1-A1|ED1-A2|EDA-A1|EDA-A2|EDA1|EDA2|HED|HED1|ODT1|STHAGX1|TNLG7C|XHED|XLHED Chromosome: chrX Strand: + Coordinate: Start Site(bp): 69616067 End Site(bp): 70039469 Gene Summary: The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000158813 HGNC ID: HGNC:3157 Entrez Gene: 1896

Expression Profile of EDA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO YES hsa-miR-107 YES NO YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-186-5p YES YES YES hsa-miR-195-5p YES NO YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-342-3p NO YES YES hsa-miR-424-5p YES NO YES hsa-miR-454-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES NO YES hsa-miR-873-5p YES YES NO Display: