ctcRbase

Entry Detail

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General Information

Database ID: BRCA04748 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DHCR24 Full Name: 24-dehydrocholesterol reductase Category: mRNA Synonyms: DCE|Nbla03646|SELADIN1|seladin-1 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 54849633 End Site(bp): 54887218 Gene Summary: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000116133 HGNC ID: HGNC:2859 Entrez Gene: 1718

Expression Profile of DHCR24 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-183-5p YES YES NO hsa-miR-191-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-205-5p YES NO YES hsa-miR-211-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-506-3p YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-760 YES NO YES hsa-miR-96-5p YES YES YES Display: