ctcRbase

Entry Detail

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General Information

Database ID: BRCA04794 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: UBE2K Full Name: ubiquitin conjugating enzyme E2 K Category: mRNA Synonyms: E2-25K|HIP2|HYPG|LIG|UBC1 Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 39698044 End Site(bp): 39782792 Gene Summary: The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000078140 HGNC ID: HGNC:4914 Entrez Gene: 3093

Expression Profile of UBE2K Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p NO YES YES hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-137 NO YES YES hsa-miR-147a YES NO NO hsa-miR-153-3p NO YES YES hsa-miR-15a-5p NO YES YES hsa-miR-15b-5p NO YES YES hsa-miR-16-5p NO YES YES hsa-miR-186-5p YES NO YES hsa-miR-195-5p NO YES YES hsa-miR-205-5p YES YES NO hsa-miR-23a-3p NO YES YES hsa-miR-23b-3p NO YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-29a-3p NO YES YES hsa-miR-29b-3p NO YES YES hsa-miR-29c-3p NO YES YES hsa-miR-31-5p YES YES YES hsa-miR-328-3p YES YES NO hsa-miR-361-5p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-424-5p NO YES YES hsa-miR-455-5p YES NO YES hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-497-5p NO YES YES Display: