ctcRbase

Entry Detail

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General Information

Database ID: BRCA04857 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SPPL2A Full Name: signal peptide peptidase like 2A Category: mRNA Synonyms: IMP3|PSL2 Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 50702266 End Site(bp): 50765808 Gene Summary: This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012] External Links: Ensembl ID: ENSG00000138600 HGNC ID: HGNC:30227 Entrez Gene: 84888

Expression Profile of SPPL2A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-219a-5p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO Display: