Entry Detail



General Information

Database ID:BRCA04883
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:LYRM1
Full Name:LYR motif containing 1
Category:mRNA
Synonyms:A211C6.1
Chromosome:chr16
Strand:+
Coordinate:
Start Site(bp):20899868End Site(bp):20925006
Gene Summary:The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
External Links:
Ensembl ID:ENSG00000102897
HGNC ID:HGNC:25074
Entrez Gene:57149



Expression Profile of LYRM1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
NO
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-1297
YES
YES
NO
hsa-miR-134-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-24-3p
YES
NO
YES
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-299-5p
YES
NO
YES
hsa-miR-329-3p
YES
YES
NO
hsa-miR-362-3p
YES
YES
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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