ctcRbase

Entry Detail

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General Information

Database ID: BRCA04953 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: IMPDH1 Full Name: inosine monophosphate dehydrogenase 1 Category: mRNA Synonyms: IMPD|IMPD1|IMPDH-I|LCA11|RP10|sWSS2608 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 128392277 End Site(bp): 128410252 Gene Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] External Links: Ensembl ID: ENSG00000106348 HGNC ID: HGNC:6052 Entrez Gene: 3614

Expression Profile of IMPDH1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-100-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-149-5p YES NO NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-324-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-665 YES NO YES hsa-miR-708-5p YES YES NO hsa-miR-99a-5p YES YES NO hsa-miR-99b-5p YES YES NO Display: