ctcRbase

Entry Detail

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General Information

Database ID: BRCA04963 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: HNRNPD Full Name: heterogeneous nuclear ribonucleoprotein D Category: mRNA Synonyms: AUF1|AUF1A|HNRPD|P37|hnRNPD0 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 82352498 End Site(bp): 82374503 Gene Summary: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000138668 HGNC ID: HGNC:5036 Entrez Gene: 3184

Expression Profile of HNRNPD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-146a-5p YES YES YES hsa-miR-146b-5p YES YES YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-384 YES YES YES hsa-miR-425-5p YES YES YES hsa-miR-429 YES NO YES hsa-miR-433-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-876-5p YES YES NO Display: