ctcRbase

Entry Detail

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General Information

Database ID: BRCA05013 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SEC63 Full Name: SEC63 homolog, protein translocation regulator Category: mRNA Synonyms: DNAJC23|ERdj2|PCLD2|PRO2507|SEC63L Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 107867756 End Site(bp): 107958189 Gene Summary: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000025796 HGNC ID: HGNC:21082 Entrez Gene: 11231

Expression Profile of SEC63 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-2-3p YES NO YES hsa-miR-1297 YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-141-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-192-5p YES YES NO hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-200a-3p YES YES NO hsa-miR-206 YES YES YES hsa-miR-215-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-299-5p YES NO YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-326 YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p NO YES YES hsa-miR-361-5p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-383-5p YES YES YES hsa-miR-411-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-501-3p YES NO YES hsa-miR-502-3p YES NO YES hsa-miR-505-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-613 YES YES YES hsa-miR-655-3p YES NO YES Display: