Entry Detail



General Information

Database ID:BRCA05094
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:GRB7
Full Name:growth factor receptor bound protein 7
Category:mRNA
Synonyms:-
Chromosome:chr17
Strand:+
Coordinate:
Start Site(bp):39737927End Site(bp):39747291
Gene Summary:The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
External Links:
Ensembl ID:ENSG00000141738
HGNC ID:HGNC:4567
Entrez Gene:2886



Expression Profile of GRB7 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-195-5p
YES
YES
NO
hsa-miR-424-5p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
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