ctcRbase

Entry Detail

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General Information

Database ID: BRCA05109 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: MTHFS Full Name: methenyltetrahydrofolate synthetase Category: mRNA Synonyms: HsT19268 Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 79833585 End Site(bp): 79897379 Gene Summary: The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] External Links: Ensembl ID: ENSG00000136371 HGNC ID: HGNC:7437 Entrez Gene: 10588

Expression Profile of MTHFS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-136-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-410-3p YES YES NO Display: