ctcRbase

Entry Detail

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General Information

Database ID: BRCA05197 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: DNAJC24 Full Name: DnaJ heat shock protein family (Hsp40) member C24 Category: mRNA Synonyms: DPH4|JJJ3|ZCSL3 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 31369840 End Site(bp): 31431849 Gene Summary: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008] External Links: Ensembl ID: ENSG00000170946 HGNC ID: HGNC:26979 Entrez Gene: 120526

Expression Profile of DNAJC24 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-7-5p YES YES NO Display: