ctcRbase

Entry Detail

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General Information

Database ID: BRCA05263 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PCMT1 Full Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase Category: mRNA Synonyms: PIMT Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 149749443 End Site(bp): 149811420 Gene Summary: This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] External Links: Ensembl ID: ENSG00000120265 HGNC ID: HGNC:8728 Entrez Gene: 5110

Expression Profile of PCMT1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-1271-5p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-194-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-217 YES YES YES hsa-miR-219a-5p YES NO YES hsa-miR-223-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-361-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-425-5p YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-96-5p YES YES YES Display: