ctcRbase

Entry Detail

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General Information

Database ID: BRCA05274 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: SCARB2 Full Name: scavenger receptor class B member 2 Category: mRNA Synonyms: AMRF|CD36L2|EPM4|HLGP85|LGP85|LIMP-2|LIMPII|SR-BII Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 76158733 End Site(bp): 76234536 Gene Summary: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] External Links: Ensembl ID: ENSG00000138760 HGNC ID: HGNC:1665 Entrez Gene: 950

Expression Profile of SCARB2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES NO YES hsa-miR-10b-5p YES NO YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-141-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-187-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-219a-5p YES YES YES hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES YES hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-342-3p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-542-3p YES YES YES hsa-miR-590-5p YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-708-5p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-876-5p YES YES YES Display: