| ncRNA Symbol: | FOS | | Full Name: | Fos proto-oncogene, AP-1 transcription factor subunit | | Category: | mRNA | | Synonyms: | AP-1|C-FOS|p55 | | Chromosome: | chr14 | | Strand: | + | | Coordinate: | | Start Site(bp): | 75278774 | End Site(bp): | 75282230 | | | Gene Summary: | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008] | | External Links: | |
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