ctcRbase

Entry Detail

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General Information

Database ID: BRCA05310 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PCNA Full Name: proliferating cell nuclear antigen Category: mRNA Synonyms: ATLD2 Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 5114953 End Site(bp): 5126626 Gene Summary: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000132646 HGNC ID: HGNC:8729 Entrez Gene: 5111

Expression Profile of PCNA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-98-5p YES YES NO Display: