ctcRbase

Entry Detail

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General Information

Database ID: BRCA05346 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: PGD Full Name: phosphogluconate dehydrogenase Category: mRNA Synonyms: 6PGD Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 10398592 End Site(bp): 10420144 Gene Summary: 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015] External Links: Ensembl ID: ENSG00000142657 HGNC ID: HGNC:8891 Entrez Gene: 5226

Expression Profile of PGD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-206 YES YES YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-613 YES YES YES Display: