ctcRbase

Entry Detail

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General Information

Database ID: BRCA05426 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: LLGL2 Full Name: LLGL scribble cell polarity complex component 2 Category: mRNA Synonyms: HGL|Hugl-2|LGL2 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 75525080 End Site(bp): 75575208 Gene Summary: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000073350 HGNC ID: HGNC:6629 Entrez Gene: 3993

Expression Profile of LLGL2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-142-3p YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-339-5p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-543 YES YES NO Display: