ctcRbase

Entry Detail

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General Information

Database ID: BRCA05463 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: OGT Full Name: O-linked N-acetylglucosamine (GlcNAc) transferase Category: mRNA Synonyms: HINCUT-1|HRNT1|MRX106|O-GLCNAC|OGT1 Chromosome: chrX Strand: + Coordinate: Start Site(bp): 71533083 End Site(bp): 71575897 Gene Summary: This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000147162 HGNC ID: HGNC:8127 Entrez Gene: 8473

Expression Profile of OGT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-1297 YES YES NO hsa-miR-140-5p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-154-5p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES NO YES hsa-miR-195-5p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-204-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-24-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES NO YES hsa-miR-376c-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-483-3p YES NO YES hsa-miR-485-5p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-501-3p YES NO YES hsa-miR-502-3p YES NO YES hsa-miR-599 YES YES NO hsa-miR-665 YES NO YES hsa-miR-7-5p YES YES YES hsa-miR-875-5p YES YES NO hsa-miR-876-5p YES YES YES hsa-miR-96-5p YES YES YES Display: