Entry Detail



General Information

Database ID:BRCA05476
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:FST
Full Name:follistatin
Category:mRNA
Synonyms:FS
Chromosome:chr5
Strand:+
Coordinate:
Start Site(bp):53480409End Site(bp):53487134
Gene Summary: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000134363
HGNC ID:HGNC:3971
Entrez Gene:10468



Expression Profile of FST Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1271-5p
YES
YES
YES
hsa-miR-129-5p
YES
YES
NO
hsa-miR-134-5p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-143-3p
YES
YES
NO
hsa-miR-182-5p
YES
YES
YES
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-33a-5p
YES
NO
YES
hsa-miR-33b-5p
YES
NO
YES
hsa-miR-505-3p
YES
YES
NO
hsa-miR-96-5p
YES
YES
YES
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