ctcRbase

Entry Detail

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General Information

Database ID: BRCA05501 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: G3BP1 Full Name: G3BP stress granule assembly factor 1 Category: mRNA Synonyms: G3BP|HDH-VIII Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 151771045 End Site(bp): 151812785 Gene Summary: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000145907 HGNC ID: HGNC:30292 Entrez Gene: 10146

Expression Profile of G3BP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-145-5p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-217 YES YES YES hsa-miR-223-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-329-3p YES NO YES hsa-miR-362-3p YES NO YES hsa-miR-381-3p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES YES hsa-miR-506-3p YES YES YES hsa-miR-543 YES YES NO Display: