ctcRbase

Entry Detail

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General Information

Database ID: BRCA05522 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PPARG Full Name: peroxisome proliferator activated receptor gamma Category: mRNA Synonyms: CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 12287368 End Site(bp): 12434356 Gene Summary: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000132170 HGNC ID: HGNC:9236 Entrez Gene: 5468

Expression Profile of PPARG Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-128-3p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-144-3p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-96-5p YES YES NO Display: