ctcRbase

Entry Detail

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General Information

Database ID: BRCA05523 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: COPS4 Full Name: COP9 signalosome subunit 4 Category: mRNA Synonyms: CSN4|SGN4 Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 83034447 End Site(bp): 83075818 Gene Summary: This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] External Links: Ensembl ID: ENSG00000138663 HGNC ID: HGNC:16702 Entrez Gene: 51138

Expression Profile of COPS4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-136-5p YES YES YES hsa-miR-154-5p NO YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-191-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-338-3p YES YES YES hsa-miR-370-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-590-5p YES YES NO Display: