ctcRbase

Entry Detail

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General Information

Database ID: BRCA05546 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HDAC2 Full Name: histone deacetylase 2 Category: mRNA Synonyms: HD2|RPD3|YAF1 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 113933028 End Site(bp): 114011308 Gene Summary: This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] External Links: Ensembl ID: ENSG00000196591 HGNC ID: HGNC:4853 Entrez Gene: 3066

Expression Profile of HDAC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-186-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-489-3p YES NO YES hsa-miR-490-3p YES YES YES hsa-miR-494-3p YES YES NO Display: