ctcRbase

Entry Detail

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General Information

Database ID: BRCA05552 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HDAC1 Full Name: histone deacetylase 1 Category: mRNA Synonyms: GON-10|HD1|RPD3|RPD3L1 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 32292086 End Site(bp): 32333635 Gene Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000116478 HGNC ID: HGNC:4852 Entrez Gene: 3065

Expression Profile of HDAC1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-371a-5p YES NO YES hsa-miR-410-3p YES YES YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-874-3p YES YES YES Display: