Entry Detail



General Information

Database ID:BRCA05610
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:AHCY
Full Name:adenosylhomocysteinase
Category:mRNA
Synonyms:SAHH|adoHcyase
Chromosome:chr20
Strand:-
Coordinate:
Start Site(bp):34280268End Site(bp):34311802
Gene Summary:S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
External Links:
Ensembl ID:ENSG00000101444
HGNC ID:HGNC:343
Entrez Gene:191



Expression Profile of AHCY Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-132-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
YES
hsa-miR-212-3p
YES
YES
NO
hsa-miR-296-3p
YES
YES
YES
hsa-miR-340-5p
YES
YES
NO
hsa-miR-370-3p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-543
YES
YES
YES
hsa-miR-758-3p
YES
YES
YES
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