ctcRbase

Entry Detail

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General Information

Database ID: BRCA05688 Cancer Type: breast cancer Dataset: GSE111842 CTCs/CTM Isolation Method: immunomagnetic FACS

Gene Information

ncRNA Symbol: REL Full Name: REL proto-oncogene, NF-kB subunit Category: mRNA Synonyms: C-Rel Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 60881521 End Site(bp): 60931610 Gene Summary: This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] External Links: Ensembl ID: ENSG00000162924 HGNC ID: HGNC:9954 Entrez Gene: 5966

Expression Profile of REL Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-382-5p YES YES NO Display: