ctcRbase

Entry Detail

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General Information

Database ID: BRCA05758 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PRKAG1 Full Name: protein kinase AMP-activated non-catalytic subunit gamma 1 Category: mRNA Synonyms: AMPKG Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 49002274 End Site(bp): 49019197 Gene Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000181929 HGNC ID: HGNC:9385 Entrez Gene: 5571

Expression Profile of PRKAG1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-383-5p YES YES YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-7-5p YES NO YES hsa-miR-873-5p YES YES NO hsa-miR-874-3p YES NO YES Display: