ctcRbase

Entry Detail

---



General Information

Database ID: BRCA05771 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: EDN1 Full Name: endothelin 1 Category: mRNA Synonyms: ARCND3|ET1|HDLCQ7|PPET1|QME Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 12290363 End Site(bp): 12297194 Gene Summary: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000078401 HGNC ID: HGNC:3176 Entrez Gene: 1906

Expression Profile of EDN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-194-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-376c-3p YES YES YES hsa-miR-379-5p YES YES YES hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-455-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-613 YES YES YES hsa-miR-98-5p YES YES YES Display: