Entry Detail



General Information

Database ID:BRCA05788
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:MARK2
Full Name:microtubule affinity regulating kinase 2
Category:mRNA
Synonyms:EMK-1|EMK1|PAR-1|Par-1b|Par1b
Chromosome:chr11
Strand:+
Coordinate:
Start Site(bp):63838928End Site(bp):63911019
Gene Summary:This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
External Links:
Ensembl ID:ENSG00000072518
HGNC ID:HGNC:3332
Entrez Gene:2011



Expression Profile of MARK2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-138-5p
NO
YES
YES
hsa-miR-183-5p
NO
YES
YES
hsa-miR-19a-3p
YES
NO
YES
hsa-miR-19b-3p
YES
NO
YES
hsa-miR-326
YES
YES
NO
hsa-miR-329-3p
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-362-3p
YES
YES
NO
hsa-miR-365a-3p
NO
YES
YES
hsa-miR-543
NO
YES
YES
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