ctcRbase

Entry Detail

---



General Information

Database ID: BRCA05804 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: NDRG1 Full Name: N-myc downstream regulated 1 Category: mRNA Synonyms: CAP43|CMT4D|DRG-1|DRG1|GC4|HMSNL|NDR1|NMSL|PROXY1|RIT42|RTP|TARG1|TDD5 Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 133237171 End Site(bp): 133302022 Gene Summary: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] External Links: Ensembl ID: ENSG00000104419 HGNC ID: HGNC:7679 Entrez Gene: 10397

Expression Profile of NDRG1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES NO YES hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-300 YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-9-5p YES NO YES hsa-miR-96-5p YES NO YES Display: