ctcRbase

Entry Detail

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General Information

Database ID: BRCA05814 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SNAP23 Full Name: synaptosome associated protein 23 Category: mRNA Synonyms: HsT17016|SNAP-23|SNAP23A|SNAP23B Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 42491233 End Site(bp): 42545356 Gene Summary: Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000092531 HGNC ID: HGNC:11131 Entrez Gene: 8773

Expression Profile of SNAP23 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-1271-5p YES NO YES hsa-miR-140-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES NO NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-421 YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-93-5p YES YES NO hsa-miR-9-5p YES NO YES hsa-miR-96-5p YES NO YES hsa-miR-98-5p YES YES YES Display: