ctcRbase

Entry Detail

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General Information

Database ID: BRCA05815 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: MGLL Full Name: monoglyceride lipase Category: mRNA Synonyms: HU-K5|HUK5|MAGL|MGL Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 127689062 End Site(bp): 127823250 Gene Summary: This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] External Links: Ensembl ID: ENSG00000074416 HGNC ID: HGNC:17038 Entrez Gene: 11343

Expression Profile of MGLL Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-137 YES NO YES hsa-miR-142-3p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-25-3p YES NO YES hsa-miR-32-5p YES NO YES hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-423-5p YES NO YES hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES hsa-miR-93-5p YES YES NO hsa-miR-98-5p YES NO YES Display: