ctcRbase

Entry Detail

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General Information

Database ID: BRCA05828 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: EI24 Full Name: EI24, autophagy associated transmembrane protein Category: mRNA Synonyms: EPG4|PIG8|TP53I8 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 125569216 End Site(bp): 125584687 Gene Summary: This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014] External Links: Ensembl ID: ENSG00000149547 HGNC ID: HGNC:13276 Entrez Gene: 9538

Expression Profile of EI24 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES NO YES hsa-miR-129-5p YES YES YES hsa-miR-182-5p YES NO YES hsa-miR-183-5p YES YES YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-379-5p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-489-3p YES NO YES hsa-miR-490-3p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-96-5p YES NO YES Display: