ctcRbase

Entry Detail

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General Information

Database ID: BRCA05834 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: HOXA5 Full Name: homeobox A5 Category: mRNA Synonyms: HOX1|HOX1.3|HOX1C Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 27141052 End Site(bp): 27143668 Gene Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000106004 HGNC ID: HGNC:5106 Entrez Gene: 3202

Expression Profile of HOXA5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-224-5p YES YES YES hsa-miR-24-3p YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES YES hsa-miR-433-3p YES YES YES hsa-miR-454-3p YES YES YES hsa-miR-599 YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-96-5p YES YES YES Display: