ctcRbase

Entry Detail

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General Information

Database ID: BRCA05855 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: RELA Full Name: RELA proto-oncogene, NF-kB subunit Category: mRNA Synonyms: NFKB3|p65 Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 65653596 End Site(bp): 65663094 Gene Summary: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] External Links: Ensembl ID: ENSG00000173039 HGNC ID: HGNC:9955 Entrez Gene: 5970

Expression Profile of RELA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p NO YES YES hsa-miR-138-5p NO YES YES hsa-miR-28-5p NO YES YES hsa-miR-302a-3p NO YES YES hsa-miR-302b-3p NO YES YES hsa-miR-302c-3p NO YES YES hsa-miR-302d-3p NO YES YES hsa-miR-302e NO YES YES hsa-miR-372-3p NO YES YES hsa-miR-373-3p NO YES YES hsa-miR-520a-3p NO YES YES hsa-miR-520b NO YES YES hsa-miR-520c-3p NO YES YES hsa-miR-520d-3p NO YES YES hsa-miR-520e NO YES YES hsa-miR-708-5p NO YES YES Display: