ctcRbase

Entry Detail

---



General Information

Database ID: BRCA05866 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: PCM1 Full Name: pericentriolar material 1 Category: mRNA Synonyms: PTC4|RET/PCM-1 Chromosome: chr8 Strand: + Coordinate: Start Site(bp): 17922840 End Site(bp): 18029944 Gene Summary: The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000078674 HGNC ID: HGNC:8727 Entrez Gene: 5108

Expression Profile of PCM1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-496 YES YES NO hsa-miR-7-5p YES YES NO Display: