ctcRbase

Entry Detail

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General Information

Database ID: BRCA05880 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: IL1B Full Name: interleukin 1 beta Category: mRNA Synonyms: IL-1|IL1-BETA|IL1F2 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 112829751 End Site(bp): 112836903 Gene Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000125538 HGNC ID: HGNC:5992 Entrez Gene: 3553

Expression Profile of IL1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-590-5p YES YES NO Display: