ctcRbase

Entry Detail

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General Information

Database ID: BRCA05921 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: HAT1 Full Name: histone acetyltransferase 1 Category: mRNA Synonyms: KAT1 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 171922448 End Site(bp): 171983682 Gene Summary: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009] External Links: Ensembl ID: ENSG00000128708 HGNC ID: HGNC:4821 Entrez Gene: 8520

Expression Profile of HAT1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-452-5p YES NO YES hsa-miR-486-5p YES YES YES Display: