ctcRbase

Entry Detail

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General Information

Database ID: BRCA05949 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: USP10 Full Name: ubiquitin specific peptidase 10 Category: mRNA Synonyms: UBPO Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 84699978 End Site(bp): 84779922 Gene Summary: Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013] External Links: Ensembl ID: ENSG00000103194 HGNC ID: HGNC:12608 Entrez Gene: 9100

Expression Profile of USP10 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-138-5p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-149-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-7-5p YES YES NO Display: