Entry Detail



General Information

Database ID:BRCA05955
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:U2AF1
Full Name:U2 small nuclear RNA auxiliary factor 1
Category:mRNA
Synonyms:FP793|RN|RNU2AF1|U2AF35|U2AFBP
Chromosome:chr21
Strand:-
Coordinate:
Start Site(bp):43092956End Site(bp):43107587
Gene Summary:This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000160201
HGNC ID:HGNC:12453
Entrez Gene:7307



Expression Profile of U2AF1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-133a-3p
YES
YES
NO
hsa-miR-133b
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
Display: