ctcRbase

Entry Detail

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General Information

Database ID: BRCA05964 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: BCAT1 Full Name: branched chain amino acid transaminase 1 Category: mRNA Synonyms: BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 24810022 End Site(bp): 24949459 Gene Summary: This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010] External Links: Ensembl ID: ENSG00000060982 HGNC ID: HGNC:976 Entrez Gene: 586

Expression Profile of BCAT1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-124-3p YES NO YES hsa-miR-125a-5p YES NO YES hsa-miR-125b-5p YES NO YES hsa-miR-1297 YES NO YES hsa-miR-130a-3p YES NO YES hsa-miR-130b-3p YES NO YES hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-146b-5p YES YES NO hsa-miR-155-5p YES NO YES hsa-miR-186-5p YES NO YES hsa-miR-196a-5p YES NO YES hsa-miR-196b-5p YES NO YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES NO YES hsa-miR-25-3p YES YES NO hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-301a-3p YES NO YES hsa-miR-301b-3p YES NO YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-339-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-374a-5p YES NO YES hsa-miR-374b-5p YES NO YES hsa-miR-454-3p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-506-3p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-98-5p YES YES YES Display: